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J Thorac Cardiovasc Surg 2008;136:241-242
© 2008 The American Association for Thoracic Surgery

Letter to the Editor

Factors predicting poor survival after resection of stage IA non–small cell lung cancer

^a Lung Cancer Unit, National Cancer Research Institute, Genoa, Italy
^b Surgical Pathology Unit, Catholic University, Rome, Italy
^c Respiratory Unit, IRCCS "San Raffaele", Rome, Italy

The first 20% of the full text of this article appears below.

To the Editor:

We have read with interest the paper by Chang and associates.¹ Interestingly, we observe that the factors considered to predict poor survival after resection of stage IA non–small cell lung cancer (NSCLC) still remain tumor size, gender, age, and extent of resection.

It is true, in fact, that lung cancer staging currently rests on histopathologic and clinical criteria that have only limited power to predict relapse and survival. A major effort to improve the control of NSCLC entails the use of molecular profiling to characterize tumors and provide accurate predictions of the outcome after standard or novel treatments. Moreover, molecular profiling, as we² already discussed . . . [Full Text of this Article]