J Thorac Cardiovasc Surg 2008;136:565
© 2008 The American Association for Thoracic Surgery
Discussion
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Dr Joseph H. Gorman
(Philadelphia, Penn). That was a good talk, Tom. Another good study from your group.
I thought the most interesting aspect of this study was your ability—if you take your results in conjunction with the work that both your group and our group have done over the years studying ischemic MR in this model—you really, you get a sense of what the contribution of the MR is as compared to what the infarct effect is during the remodeling process that leads to heart failure. And if you looked at your data here, which is pure MR, the systolic volume increases by about 20% acutely and then really doesn't increase at all significantly over 12 weeks. If you look at this model when you give them a posterior infarct and they develop ischemic MR over 12 weeks, their . . . [Full Text of this Article]
Copyright © 2008 by The American Association for Thoracic Surgery.