J Thorac Cardiovasc Surg 2008;136:1104
© 2008 The American Association for Thoracic Surgery
Aprotinin and renal dysfunction: The role of exposure to angiotensin-converting enzyme inhibitors
John G.T. Augoustides, MD, FASE
Associate Professor, Department of Anesthesiology and Critical Care, Hospital of the University of Pennsylvania, Philadelphia, PA 19104-4283
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To the Editor:
I read with great interest the recent article by Pagano and colleagues1 detailing their favorable experience with aprotinin in a large patient series (N = 7836: 1998–2006) from a single institution. The authors demonstrated that aprotinin exposure did not significantly affect the incidence of postoperative renal dysfunction.
Careful review of . . . [Full Text of this Article]
Copyright © 2008 by The American Association for Thoracic Surgery.