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J Thorac Cardiovasc Surg 2008;136:1105-1106
© 2008 The American Association for Thoracic Surgery

Letter to the Editor

Optimizing selective cerebral perfusion in adult aortic arch repair: Clinical relevance of the laboratory model

Associate Professor, Department of Anesthesiology and Critical Care, Hospital of the University of Pennsylvania, Philadelphia, PA 19104-4283

The first 20% of the full text of this article appears below.

To the Editor:

I read with great interest the excellent article by Halstead and colleagues¹ detailing in their porcine model of deep hypothermic circulatory arrest (DHCA) the neuroprotective effects of selective cerebral perfusion (SCP) via both carotid arteries at a mean of 50 mm Hg for a period of 90 minutes. In this laboratory model, the authors have clearly demonstrated the adverse cerebral effects associated with SCP at higher pressures . . . [Full Text of this Article]