JTCS Click here to go to SJM website.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to Personal Folders
Right arrow Download to citation manager
Right arrow Author home page(s):
Michael L. Dewar
Right arrow Permission Requests
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ozcan, C.
Right arrow Articles by Rosenfeld, L. E.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Ozcan, C.
Right arrow Articles by Rosenfeld, L. E.
Related Collections
Right arrow Valve disease

J Thorac Cardiovasc Surg 2009;137:239-241
© 2009 The American Association for Thoracic Surgery

Brief Communication

An unusual case of nonbacterial thrombotic (marantic) endocarditis

Cevher Ozcan, MD, Edward J. Miller, MD, Kerry S. Russell, MD, PhD, Michael L. Dewar, MD, Lynda E. Rosenfeld, MD*

Section of Cardiovascular Medicine, Yale University School of Medicine, New Haven, Conn

Received for publication December 13, 2007; revisions received January 3, 2008; accepted for publication January 20, 2008.

* Address for reprints: Lynda E. Rosenfeld, MD, Section of Cardiovascular Medicine 3FMP, Yale University School of Medicine, 333 Cedar St, New Haven, CT 06510. (Email: lynda.rosenfeld@yale.edu).

The first 20% of the full text of this article appears below.

Nonbacterial thrombotic (marantic) endocarditis (NBTE) is a rare clinical condition manifest as various-sized cardiac valvular lesions ranging from microscopic aggregates of platelets to large vegetations of fibrin and platelets. It is difficult to diagnose NBTE before death. Despite significant advances in noninvasive diagnostic techniques, definitive diagnosis requires a tissue biopsy. We present an unusual case of NBTE with a large subvalvular mass invading the left ventricular posterior wall and papillary muscles and causing mitral stenosis. In this case, the final diagnosis was only made at the time of therapeutic surgical excision of the mass and mitral valve replacement.

Clinical Summary

A 30-year-old woman with a history of aplastic anemia and an HLA-matched allogenic stem cell transplantation 2 years before admission had fever and hypoxemia. On physical examination she had diffuse rales and a diastolic murmur. Her course had been complicated by chronic graft-versus-host disease (GVHD) with fasciitis, treated with prednisone and sirolimus. Computed tomography of the chest revealed pulmonary edema with bilateral pleural effusions and superimposed pneumonia. Blood cultures were sterile. Tests for the human immunodeficiency virus, cytomegalovirus, Epstein-Barr virus, Q fever, Chlamydia, Mycoplasma, Bartonella, . . . [Full Text of this Article]






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
ANN THORAC SURG ASIAN CARDIOVASC THORAC ANN EUR J CARDIOTHORAC SURG
J THORAC CARDIOVASC SURG ICVTS ALL CTSNet JOURNALS
Copyright © 2009 by The American Association for Thoracic Surgery.