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J Thorac Cardiovasc Surg 2009;137:1273-1275
© 2009 The American Association for Thoracic Surgery


Brief Communication

Early calcification of a stentless pericardial bioprosthesis in the elderly

Maria Grazia Croccia, MDa, Stefano Pratali, MDa, Cristina Basso, MD, PhDb, Giovanni Scioti, MDa, Mila Della Barbera, BSc, PhDb, Gaetano Thiene, MDb, Uberto Bortolotti, MDa,*

a Section of Cardiac Surgery, University of Pisa Medical School, Pisa, Italy
b Cardiovascular Pathology, University of Padova Medical School, Padova, Italy

Received for publication February 28, 2008; accepted for publication March 8, 2008.

* Address for reprints: Uberto Bortolotti, MD, Sezione Autonoma di Cardiochirurgia Universitaria, Dipartimento Cardiotoracico e Vascolare, Via Paradisa 2, 56124 Pisa, Italy. (Email: u.bortolotti@cardchir.med.unipi.it).

The first 20% of the full text of this article appears below.

The Sorin Freedom pericardial valve (SFP, Sorin BiomedicaCardio, Saluggia, Italy), a stentless bioprosthesis made of glutaraldehyde-tanned bovine pericardium, was introduced clinically in 1991.1Go In 2000, detoxification treatment with homocysteic acid was added to eliminate glutaraldehyde toxicity and mitigate tissue calcification. The SFP has shown excellent overall results at medium term with no cases of structural failure.2Go We report the first case of early SFP calcification in an elderly recipient.

Clinical Summary

An 84-year-old woman underwent aortic valve replacement in 2000 with a 25-mm SFP, implanted with 3 continuous sutures of 4-0 polypropylene to secure the inflow and outflow rims; . . . [Full Text of this Article]







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