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J Thorac Cardiovasc Surg 2009;137:1565-1568
© 2009 The American Association for Thoracic Surgery

Brief Communication

A new miniaturized cardiopulmonary bypass system reduces transfusion requirements during neonatal cardiac surgery: Initial experience in 13 consecutive patients

^a Department of Anesthesia, Deutsches Herzzentrum Berlin, Berlin, Germany
^b Department of Cardiovascular and Thoracic Surgery, Deutsches Herzzentrum Berlin, Berlin, Germany
^c Department of Perfusion, Deutsches Herzzentrum Berlin, Berlin, Germany
^d Department of Cogenital Heart Disease, Deutsches Herzzentrum Berlin, Berlin, Germany

Received for publication January 8, 2008; revisions received February 20, 2008; accepted for publication March 18, 2008.

^_* Address for reprints: Andreas Koster, MD, Department of Anesthesia, Deutsches Herzzentrum Berlin, Augustenburger Platz 1, D-13353 Berlin, Germany. (Email: koster@dhzb.de).

The first 20% of the full text of this article appears below.

The potential detrimental effects of the transfusion of autologous blood products on patients' outcome is increasingly appreciated.^1,2 This has promoted strategies to reduce the consumption of donor blood products, as well as investigations assessing lower "critical" hemoglobin values as a trigger for transfusions.³ However, particularly in small infants and neonates, the goal of transfusion-free cardiovascular surgery is usually limited by the extreme hemodilution caused by the relatively large priming volume of the cardiopulmonary bypass (CPB) system. During recent years, we have demonstrated that implementation of small components in the CPB circuit resulting in reduction of the CPB priming volume facilitated transfusion-free cardiovascular surgery in selected cases in neonates and small infants.⁴ Here we report our first experiences with a new miniature oxygenator and arterial filter system that further significantly reduces the priming volume of our neonatal CPB circuit.

Clinical Summary

After approval by the local ethics committee and having obtained informed consent from the parents, we analyzed the data of 13 consecutive neonates (age 28 days) who underwent cardiovascular surgery at our institution with the new CPB setup.

The new CPB system differs from our previously described . . . [Full Text of this Article]

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				A. Koster, M. Huebler, and R. Hetzer Reply to the editor. J. Thorac. Cardiovasc. Surg., December 1, 2009; 138(6): 1454 - 1455. [Full Text] [PDF]