J Thorac Cardiovasc Surg 2009;138:262
© 2009 The American Association for Thoracic Surgery
Mechanism of myocardial protection by pressure-volume unloading involves stretch-induced pathophysiology
Alfred C. Nicolosi, MD
Division of Cardiothoracic Surgery, Medical College of Wisconsin, Milwaukee, Wis
|The first 20% of the full text of this article appears below.|
To the Editor:
I read with interest the recent report by Tamareille and colleagues,1 who demonstrate in a porcine model of myocardial infarction that left ventricular (LV) unloading with a left ventricular assist device (LVAD) during early reperfusion is associated with both reduced endothelin-1 release by the myocardium and reduced infarct size. They demonstrate a positive . . . [Full Text of this Article]
Left ventricular unloading before reperfusion reduces endothelin-1 release and calcium overload in porcine myocardial infarction
- Sophie Tamareille, Hela Achour, James Amirian, Patricia Felli, Roger J. Bick, Brian Poindexter, Yong J. Geng, William H. Barry, and Richard W. Smalling
J. Thorac. Cardiovasc. Surg. 2008 136: 343-351.
Copyright © 2009 by The American Association for Thoracic Surgery.