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J Thorac Cardiovasc Surg 2009;138:785-786
© 2009 The American Association for Thoracic Surgery

Letter to the Editor

Pulmonary arterial hypertension and congenital heart disease: Targeted therapies and operability

Maurice Beghetti, MD, Cecile Tissot, MD

Pediatric Cardiology Unit, Department of the Child and Adolescent, Children's University Hospital of Geneva, Geneva, Switzerland

The first 20% of the full text of this article appears below.

To the Editor:

We read with great interest the case report of Hoetzenecker and colleagues1Go of a patient with severe pulmonary arterial hypertension associated with an atrial septal defect and the beneficial effect of bosentan, which allowed for closure of the defect. This is a very interesting topic that raises a lot of controversies in the field of pulmonary arterial hypertension associated with congenital heart disease.2Go

I would like to comment on the hemodynamic data presented in Table 1. Total pulmonary resistance at baseline is calculated at 460 dynes · s –1 · cm–5, but . . . [Full Text of this Article]


Related Article

Reply to the Editor
Konrad Hoetzenecker, Hendrik J. Ankersmit, and Irene M. Lang
J. Thorac. Cardiovasc. Surg. 2009 138: 786. [Extract] [Full Text] [PDF]



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