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J Thorac Cardiovasc Surg 2009;138:788-789
© 2009 The American Association for Thoracic Surgery


Letter to the Editor

Reply to the Editor

Marc R. Moon, MD

Joseph C. Bancroft Professor of Surgery, Division of Cardiothoracic Surgery, Washington University School of Medicine, Saint Louis, Mo

The first 20% of the full text of this article appears below.

I would like to thank the groups from Naples and Pittsburgh for their interest in our recent study examining the impact of prosthesis–patient mismatch (PPM) on long-term survival in patients greater than 70 years of age. It is important to note that we did not specifically investigate the role of PPM on tissue valve degeneration, but it is likely to play a role given the potential impact of pressure gradients on leaflet durability. However, as demonstrated by Fann and associates from Stanford,1Go age clearly impacts the rate of structural valve degeneration, such that even with first- and . . . [Full Text of this Article]


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