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J Thorac Cardiovasc Surg 2009;138:790-791
© 2009 The American Association for Thoracic Surgery


Letter to the Editor

A meta-analysis of controlled studies of preoperative statin therapy for prevention of postoperative mortality in cardiac surgery

Hisato Takagi, MD, PhD, Takuya Umemoto, MD, PhD

Department of Cardiovascular Surgery, Shizuoka Medical Center, Shizuoka, Japan

The first 20% of the full text of this article appears below.

To the Editor:

We read with great interest an article by Tabata and associates,1Go because we2Go previously performed a meta-analysis of controlled studies of preoperative statin therapy for postoperative mortality in cardiac surgery. Tabata and collaborators1Go showed that preoperative statin use was associated with lower mortality (adjusted odds ratio [OR], 0.25; 95% confidence interval [CI], 0.12–0.54; P = .0004) in 1389 patients without coronary artery disease who undewent cardiac surgery. Meanwhile, our previous pooled analysis of ORs from 3 randomized controlled trials and adjusted ORs from 6 observational controlled studies (representing 18,637 patients) demonstrated a statistically significant 24% . . . [Full Text of this Article]


Related Article

Reply to the Editor
Minoru Tabata
J. Thorac. Cardiovasc. Surg. 2009 138: 792. [Extract] [Full Text] [PDF]



This article has been cited by other articles:


Home page
Ann. Thorac. Surg.Home page
H. Takagi, H. Manabe, and T. Umemoto
Preoperative Statin Therapy Reduces Early Mortality in Patients Undergoing Cardiac Operations
Ann. Thorac. Surg., March 1, 2011; 91(3): 983 - 984.
[Full Text] [PDF]




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