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J Thorac Cardiovasc Surg 2009;138:1454-1455
© 2009 The American Association for Thoracic Surgery

Letter to the Editor

Reply to the Editor

Andreas Koster, MDa, Michael Huebler, MDb, Roland Hetzer, MD, PhDb

a Deutsches Herzzentrum Baden, Lahr, Germany
b Deutsches Herzzentrum Berlin, Berlin, Germany

The first 20% of the full text of this article appears below.

We thank Dr Durandy very much for her comments. We completely agree that performing transfusion-free surgery cannot be a goal in itself. There are convincing data from the adult world and first data from the pediatric world of cardiac surgery showing that transfusion of allogeneic blood impairs clinical outcomes. However, the small scale of our investigation and the great heterogeneity of cardiac malformations meant that the study was not powered to perform an assessment in this regard.

As you outlined, in addition to the technical aspects of the perfusion technique and the cardiopulmonary bypass (CPB) setup, definition of the critical hemoglobin value as a trigger for transfusion remains a key question. . . . [Full Text of this Article]


Related Article

Pediatric cardiac surgery: Effect of a miniaturized bypass circuit in reducing homologous blood transfusion
Yves Dominique Durandy
J. Thorac. Cardiovasc. Surg. 2009 138: 1454. [Extract] [Full Text] [PDF]





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