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J Thorac Cardiovasc Surg 2010;139:234-236
© 2010 The American Association for Thoracic Surgery

Letter to the Editor

Lung ventilation/perfusion may reduce pulmonary injury during cardiopulmonary bypass

Francisco Igor B. Macedo, MDa, Enisa M. Carvalhoa, Edward Gologorsky, MDb, Tomas A. Salerno, MDa

a Division of Cardiothoracic Surgery, University of Miami Miller School of Medicine and Jackson Memorial Hospital, Miami, Fla
b Department of Anesthesiology, University of Miami Miller School of Medicine and Jackson Memorial Hospital, Miami, Fla

The first 20% of the full text of this article appears below.

To the Editor:

During cardiac surgery with cardiopulmonary bypass (CPB), the surgeon is assured that all organs are perfused and/or protected. The heart—lung machine provides perfusion to all organs while the heart is either cardioplegically arrested or perfused.1Go One assumes that the lungs are perfused, although pulmonary artery blood flow, the major source of blood supply to the lungs, ceases. Discontinuation of pulsatile flow and low mean pressures further accentuate decreased bronchial artery flow. The lung is the "target" organ, especially during prolonged CPB. Severe pulmonary dysfunction, manifested as poor gas exchange, pulmonary edema, and prolonged need for artificial ventilation, are consequences.

Imura and associates2Go correlated low-frequency mechanical ventilation during CPB in pigs with suppression of . . . [Full Text of this Article]


Related Article

Reply to the Editor
Hajime Imura, Gianni D. Angelini, Saadeh M. Suleiman, and Raimondo Ascione
J. Thorac. Cardiovasc. Surg. 2010 139: 236-237. [Extract] [Full Text] [PDF]





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