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J Thorac Cardiovasc Surg 2003;125:1202-1203
© 2003 The American Association for Thoracic Surgery

Editorials

Is it time to choose amiodarone for postoperative atrial fibrillation?

From the Department of Surgery, Division of Cardiothoracic Surgery, University of Massachusetts Memorial Medical Center, Worcester, Mass.

Received for publication Dec 3, 2002. Accepted for publication Dec 16, 2002. Address for reprints: A. E. Saltman, MD, Department of Surgery, Division of Cardiothoracic Surgery, University of Massachusetts Memorial Medical Center, 55 Lake Ave N S3-747, Worcester, MA 01655 (E-mail: aesmdphd@hotmail.com).

The first 20% of the full text of this article appears below.

See related article on page 1420.

Despite the astonishing advances that have been made in cardiac surgery over the past 40 years, new-onset atrial fibrillation remains its most common complication. Long thought a nuisance, it has now been clearly shown to increase length of stay, intensive care unit utilization, morbidity, and even long-term mortality. It occurs in anywhere from 15% to 40% of patients and little progress has been made in our understanding, prevention, or treatment of it.

Yagdi and colleagues ¹ have presented elsewhere in this issue of the Journal their study on the use of amiodarone to prevent new-onset postoperative atrial fibrillation (PAF) in patients undergoing coronary artery bypass grafting. They studied a group of 157 subjects, randomly assigned to receive amiodarone after surgery or their usual care without amiodarone. The drug was administered as an intravenous infusion over 2 days, beginning immediately after surgery, followed by declining oral dosing . . . [Full Text of this Article]

Related Article

Amiodarone reduces the incidence of atrial fibrillation after coronary artery bypass grafting

Tahir Yagdi, Sanem Nalbantgil, Fatih Ayik, Anil Apaydin, Fatih Islamoglu, Hakan Posacioglu, Tanzer Calkavur, Yuksel Atay, and Suat Buket
J. Thorac. Cardiovasc. Surg. 2003 125: 1420-1425. [Abstract] [Full Text] [PDF]

This article has been cited by other articles:

				A. A. Alsaddique, A. G. Royse, C. F. Royse, and M. A. Fouda Management of diastolic heart failure following cardiac surgery Eur. J. Cardiothorac. Surg., February 1, 2009; 35(2): 241 - 249. [Abstract] [Full Text] [PDF]

				A. Yazigi, F. Haddad, S. Madi-Jebara, G. Sleilaty, and V. A. Jebara Amiodarone for postoperative atrial fibrillation J. Thorac. Cardiovasc. Surg., January 1, 2004; 127(1): 304 - 304. [Full Text] [PDF]