J Thorac Cardiovasc Surg 2007;133:737
© 2007 The American Association for Thoracic Surgery
DiscussionGeneral Thoracic Surgery: Discussion |
Discussion
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Dr Y. Joseph Woo
(Philadelphia, Pa). Does the WIF block the canonical and noncanonical Wnts or one group in particular?
Dr Kim. That is a good question. On the basis of our Western analysis, it seems that there is some inhibition of the canonical pathway because there is some decrease in ß-catenin levels. We have looked at disheveled levels as a marker of noncanonical pathways, and our results thus far have been mixed. It . . . [Full Text of this Article]
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Copyright © 2007 by The American Association for Thoracic Surgery.