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J Thorac Cardiovasc Surg 1994;108:589-590
© 1994 Mosby, Inc.


LETTERS TO THE EDITOR

Inadvertent transection of anomalously arising left anterior descending artery during tetralogy of Fallot repair: Bypass grafting with left internal mammary artery

Arun K. Bhutani, MCh, Moosekunhi M. Koppala, MCh, Kurudamannil A. Abraham, DM, Komarakshi R. Balakrishnan, MCh, Rajesh N. Desai, MCh

Department of Cardiovascular Surgery
Southern Railway Headquarters Hospital
Ayanavaram, Perambur
Madras 600023, India

To the Editor:

The tetralogy of Fallot is known to be associated with anomalous origin of the left anterior descending artery (LAD) from the right coronary artery in about 5% of patients Go Go 1,2 This abnormality is important surgically because the anomalous LAD courses across the right ventricular outflow tract, where a subpulmonic incision is usually made during a surgical repair. Also, postmortem study has shown that the anomalous artery may be buried in the myocardium. Go 3 The anomalous LAD may be divided during attempts to enlarge the outflow tract, and results of this injury have been adequately detailed by numerous reports. Go Go 4-6 We report a case of tetralogy of Fallot in which an anomalously arising LAD was transected inadvertently during intracardiac repair. Blood supply distal to the transection was restored by a left internal mammary artery (IMA) graft, which was dissected with the aid of cardiopulmonary bypass.

Tetralogy of Fallot with an LAD arising from the right coronary artery was diagnosed in an 18-year-old boy. The intracardiac repair was done with the aid of cardiopulmonary bypass with core cooling to 25° C and blood cardioplegia. The infundibular resection and pulmonary valvotomy were performed through a right atriotomy and pulmonary arteriotomy, respectively. During extension of the pulmonary arteriotomy across the anulus to the infundibulum to repair the hypoplastic anulus, the LAD was divided accidentally. After closure of the ventricular septal defect, a pericardial patch was placed on the right ventricular outflow tract with the heart beating during rewarming. The left IMA was dissected with the aid of cardiopulmonary bypass and grafted to the LAD distal to the site of transection with the aid of cardioplegic arrest. The patient was weaned from cardiopulmonary bypass with dopamine 5µg/kg per minute, started electively.

His early stay in the intensive care unit was uneventful, with good hemodynamics. A tracheostomy was done on the second postoperative day for right-sided diaphragmatic paresis caused by phrenic nerve palsy that resulted from the use of iced slush. The tracheostomy was closed on the ninth postoperative day and the patient was discharged 2 days after tracheostomy closure.

The patient was seen 3 months after the operation and is attending college. He is free of symptoms and has no evidence of infarction or ischemia on the electrocardiogram. Simultaneous IMA injection and right ventricular angiography done at 3 months show a patent left IMA, right ventricular outflow tract, and distal pulmonary arteries (Fig. 1). The left ventriculogram and echocardiogram show good left ventricular function, as well.



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Fig. 1. Digital subtraction angiogram in right anterior oblique view showing patent left IMA and pericardial transannular right ventricular outflow patch with distal pulmonary arteries.

 
Identification of an anomalously arising LAD is an indispensable part of the preoperative workup for patients with tetralogy of Fallot. Minor coronary branches can be sacrificed without any consequence during repair. Several surgical strategies have been used to protect the anomalously arising LAD. Bonchek Go 7 in 1976 described the method of dissecting the coronary artery off the outflow tract with placement of an outflow patch beneath the artery. This technique carries the risk of stretching with resultant ischemia caused by right ventricular dilatation, which is not uncommon immediately after the operation. The ventricular septal defect can be closed through the aorta if an outflow patch is not required. Go 8 A transverse ventriculotomy below the LAD can be used for relief of infundibular stenosis and closure of the ventricular septal defect. Go 6 A separate ventriculotomy can be made at or near the pulmonary anulus if a transverse ventriculotomy is inadequate. Go 5 Hurwitz and coworkers Go 9 recommended a separate pulmonary artery incision for relief of pulmonary stenosis and enlargement with a patch if necessary. Humes and coworkers Go 10 suggested using either patch reconstruction or conduit placement in this situation depending on the exact location and tortuosity of the anomalous artery and the level and severity of the right ventricular outflow tract obstruction. Castaneda and colleagues Go 11 considered this additional anomaly to be a contraindication to primary repair in infancy. The complete repair can be deferred until the child is 5 to 6 years old. The transatrial approach may be useful in the presence of this anomaly. Go 12 However, its effectiveness and usefulness are limited if the obstruction is primarily infundibular and the pulmonary valve anulus is of adequate size for body weight and surface area.

Bypass grafting is the only method of restoring blood supply distal to an inadvertently transected LAD. Berry and McGoon Go 5 were the first to report aorta-coronary bypass grafting with autologous saphenous vein in 1973. Shaffer, Berman, and Waldhausen Go 13 reported another case of saphenous vein grafting for divided anomalous LAD in a 13-year-old boy. Although di Carlo and colleagues Go 14 reported aorta-coronary bypass with a polytetraflouroethylene graft in a 17-month-old boy, the graft was for a transected left coronary artery. Our case represents the first use of a left IMA graft for inadvertent transection of an anomalous LAD. On the basis of various reports of use of the IMA for coronary artery disease, we predict that the patient will do well.

Preoperative angiography is important to delineate the coronary artery anomalies in tetralogy of Fallot. Various modifications may be used to prevent injury to an anomalously arising LAD. If it is damaged, the blood supply distal to the site of injury or transection can be successfully restored by bypass grafting with polytetrafluoroethylene, saphenous vein, or a left IMA graft.

References

  1. Dabizzi RP, Caprioli G, Alazzi L. Distribution and anomalies of coronary arteries in tetralogy of Fallot. Circulation 1980;61:84.[Abstract/Free Full Text]
  2. Fellows KE, Smith J, Keane JF. Preoperative angiocardiography in infants with tetrad of Fallot: review of 36 cases. Am J Cardiol 1981;47:1279.[Medline]
  3. Meng CCL, Eckner FAD, Lev M. Coronary artery distribution in tetralogy of Fallot. Arch Surg 1965;90:363.
  4. Bahnson HT, Spencer FC, Landtman B, Wolf MD, Neill CA, Taussig HB. Surgical treatment and follow-up of 147 cases of tetralogy of Fallot treated by correction. J THORAC CARDIOVASC SURG 1962;44:419.
  5. Berry BE, McGoon DC. Total correction for tetralogy of Fallot with anomalous coronary artery. Surgery 1973;74:894.[Medline]
  6. Meyer J, Chiariello L, Hallman GL, et al. Coronary artery anomalies in patients with tetralogy of Fallot. J THORAC CARDIOVASC SURG 1975;69:373.[Abstract]
  7. Bonchek LI. A method of outflow tract reconstruction in tetralogy of Fallot with anomalous anterior descending coronary artery. Ann Thorac Surg 1976;21:451.[Abstract]
  8. Cooley DA, Hallman GL, Wukasch DC, et al. Transaortic repair of ventricular septal defect. Ann Thorac Surg 1973;16:99.[Medline]
  9. Hurwitz RA, Smith W, King H, Girod DA, Caldwell RL. Tetralogy of Fallot with abnormal coronary artery: 1967 to 1977. J THORAC CARDIOVASC SURG 1980;80:129.[Abstract]
  10. Humes RA, Driscoll DJ, Danielson GK, Puga FJ. Tetralogy of Fallot with anomalous origin of left anterior descending coronary artery J THORAC CARDIOVASC SURG 1987;94:784.[Abstract]
  11. Castaneda AR, Freed MD, Williams RG, Norwood WI. Repair of tetralogy of Fallot in infancy: Early and late results. J THORAC CARDIOVASC SURG 1977;74:372.[Medline]
  12. Edmunds LH, Saxena NC, Friedman S, Rashkind WJ, Dodd PF. Transatrial repair of tetralogy of Fallot. Surgery 1976;80:681.[Medline]
  13. Shaffer CW, Berman W, Waldhausen JA. Repair of divided anomalous anterior descending coronary artery in tetralogy of Fallot. Ann Thorac Surg 1979;27:250.[Abstract]
  14. di Carlo D, De Nardo D, Ballerini L, Marcelletti C. Injury to the left coronary artery during repair of tetralogy of Fallot: successful aorta-coronary polytetrafluoroethylene graft. J THORAC CARDIOVASC SURG 1987;93:468.[Abstract]



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